The cys‐loop ligand‐gated ion channel gene superfamilies of the cockroaches <scp> <i>Blattella germanica</i> </scp> and <scp> <i>Periplaneta americana</i> </scp>

BACKGROUND Cockroaches are serious urban pests that can transfer disease-causing microorganisms as well trigger allergic reactions and asthma. They commonly managed by pesticides act on cys-loop ligand-gated ion channels (cysLGIC). To provide further information will enhance our understanding of how insecticides their molecular targets in cockroaches, we used genome reverse transcriptase polymerase chain reaction (RT-PCR) data to characterize the cysLGIC gene superfamilies from Blattella germanica Periplaneta americana. RESULTS The B. P. americana consist 30 32 subunit-encoding genes, respectively, which largest insect characterized date. As with other insects, cockroaches possess predicted be gated acetylcholine, γ-aminobutyric acid, glutamate histamine, orthologues drosophila pH-sensitive chloride channel (pHCl), CG8916 CG12344. large a result an expanded number divergent nicotinic acetylcholine receptor subunits, americana, possessing eight ten subunit genes. Diversity cockroach cysLGICs is also broadened alternative splicing RNA A-to-I editing. Unusually, both species second glutamate-gated another subunit. CONCLUSION These findings evolution superfamily useful basis for study function, detection management insecticide resistance, development improved greater specificity towards these major pests. © 2020 Society Chemical Industry